[Novel influenza H1N1/2009: virus transmission among health care worker].
Identifieur interne : 000354 ( Main/Exploration ); précédent : 000353; suivant : 000355[Novel influenza H1N1/2009: virus transmission among health care worker].
Auteurs : S. Wicker [Allemagne] ; H F Rabenau ; M. Bickel ; T. Wolf ; R. Brodt ; C. Brandt ; A. Berger ; H W Doerr ; R. LehmannSource :
- Deutsche medizinische Wochenschrift (1946) [ 1439-4413 ] ; 2009.
Descripteurs français
- KwdFr :
- Adulte, Allemagne, Femelle, Grippe humaine (), Grippe humaine (diagnostic), Grippe humaine (traitement médicamenteux), Grippe humaine (transmission), Humains, Lutte contre l'infection, Personnel de santé, Sous-type H1N1 du virus de la grippe A, Transmission de maladie infectieuse du patient au professionnel de santé.
- MESH :
- diagnostic : Grippe humaine.
- traitement médicamenteux : Grippe humaine.
- Adulte, Allemagne, Femelle, Grippe humaine, Humains, Lutte contre l'infection, Personnel de santé, Sous-type H1N1 du virus de la grippe A, Transmission de maladie infectieuse du patient au professionnel de santé.
- Wicri :
- geographic : Allemagne.
English descriptors
- KwdEn :
- MESH :
- geographic : Germany.
- diagnosis : Influenza, Human.
- drug therapy : Influenza, Human.
- prevention & control : Influenza, Human.
- transmission : Influenza, Human.
- Adult, Female, Health Personnel, Humans, Infection Control, Infectious Disease Transmission, Patient-to-Professional, Influenza A Virus, H1N1 Subtype.
Abstract
HISTORY AND ADMISSION FINDINGS
A 27-year-old female presented with fever (40 C) and infection of the upper respiratory tract in an emergency room (ER) department of our university hospital. Within the last days, she worked as a nurse in that ER, responsible for taking care of patients with novel influenza and also executing screening-examinations of suspicious cases.
INVESTIGATIONS
Patient in a reduced condition of health. C-reactive protein was significantly elevated (6.6 mg/dl - norm < 0.5). A PCR carried out on the admission day revealed a highly positive reaction (CT:19.29).
DIAGNOSIS, TREATMENT AND COURSE
Due to positive PCR laboratory report for H1N1/2009 and multiple occupational contacts with H1N1/2009 patients, therapy with neuraminidase inhibitor was started. After a five-day antiviral therapy and clinical signs of recovery, PCR was negative on the sixth treatment day.
CONCLUSION
Health care workers (HCWs) are at risk of occupational exposure to influenza. Against the backdrop of the spread of H1N1 (2009) appropriate protective measures should be implemented to reduce the risk for transmission in health-care settings. The acquisition of epidemiologic data of occupational infections in Germany ought to be optimized. Required protective measures should be evaluated with regard to practicability and effectiveness.
DOI: 10.1055/s-0029-1242012
PubMed: 19908176
Affiliations:
- Allemagne
- District de Darmstadt, Hesse (Land)
- Francfort-sur-le-Main
- Université Johann Wolfgang Goethe de Francfort-sur-le-Main
Links toward previous steps (curation, corpus...)
Le document en format XML
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Lehmann</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2009">2009</date><idno type="RBID">pubmed:19908176</idno><idno type="pmid">19908176</idno><idno type="doi">10.1055/s-0029-1242012</idno><idno type="wicri:Area/Main/Corpus">000374</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000374</idno><idno type="wicri:Area/Main/Curation">000374</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000374</idno><idno type="wicri:Area/Main/Exploration">000374</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">[Novel influenza H1N1/2009: virus transmission among health care worker].</title><author><name sortKey="Wicker, S" sort="Wicker, S" uniqKey="Wicker S" first="S" last="Wicker">S. Wicker</name><affiliation wicri:level="4"><nlm:affiliation>Betriebsärztlicher Dienst, Klinikum der Johann Wolfgang Goethe-Universität Frankfurt. Sabine.Wicker@kgu.de</nlm:affiliation><country>Allemagne</country><placeName><settlement type="city">Francfort-sur-le-Main</settlement><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region></placeName><orgName type="university">Université Johann Wolfgang Goethe de Francfort-sur-le-Main</orgName></affiliation></author><author><name sortKey="Rabenau, H F" sort="Rabenau, H F" uniqKey="Rabenau H" first="H F" last="Rabenau">H F Rabenau</name></author><author><name sortKey="Bickel, M" sort="Bickel, M" uniqKey="Bickel M" first="M" last="Bickel">M. Bickel</name></author><author><name sortKey="Wolf, T" sort="Wolf, T" uniqKey="Wolf T" first="T" last="Wolf">T. Wolf</name></author><author><name sortKey="Brodt, R" sort="Brodt, R" uniqKey="Brodt R" first="R" last="Brodt">R. Brodt</name></author><author><name sortKey="Brandt, C" sort="Brandt, C" uniqKey="Brandt C" first="C" last="Brandt">C. Brandt</name></author><author><name sortKey="Berger, A" sort="Berger, A" uniqKey="Berger A" first="A" last="Berger">A. Berger</name></author><author><name sortKey="Doerr, H W" sort="Doerr, H W" uniqKey="Doerr H" first="H W" last="Doerr">H W Doerr</name></author><author><name sortKey="Lehmann, R" sort="Lehmann, R" uniqKey="Lehmann R" first="R" last="Lehmann">R. Lehmann</name></author></analytic><series><title level="j">Deutsche medizinische Wochenschrift (1946)</title><idno type="eISSN">1439-4413</idno><imprint><date when="2009" type="published">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Female</term><term>Germany</term><term>Health Personnel</term><term>Humans</term><term>Infection Control</term><term>Infectious Disease Transmission, Patient-to-Professional</term><term>Influenza A Virus, H1N1 Subtype</term><term>Influenza, Human (diagnosis)</term><term>Influenza, Human (drug therapy)</term><term>Influenza, Human (prevention & control)</term><term>Influenza, Human (transmission)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Allemagne</term><term>Femelle</term><term>Grippe humaine ()</term><term>Grippe humaine (diagnostic)</term><term>Grippe humaine (traitement médicamenteux)</term><term>Grippe humaine (transmission)</term><term>Humains</term><term>Lutte contre l'infection</term><term>Personnel de santé</term><term>Sous-type H1N1 du virus de la grippe A</term><term>Transmission de maladie infectieuse du patient au professionnel de santé</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Germany</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Grippe humaine</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Grippe humaine</term></keywords><keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Female</term><term>Health Personnel</term><term>Humans</term><term>Infection Control</term><term>Infectious Disease Transmission, Patient-to-Professional</term><term>Influenza A Virus, H1N1 Subtype</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Allemagne</term><term>Femelle</term><term>Grippe humaine</term><term>Humains</term><term>Lutte contre l'infection</term><term>Personnel de santé</term><term>Sous-type H1N1 du virus de la grippe A</term><term>Transmission de maladie infectieuse du patient au professionnel de santé</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Allemagne</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>HISTORY AND ADMISSION FINDINGS</b></p><p>A 27-year-old female presented with fever (40 C) and infection of the upper respiratory tract in an emergency room (ER) department of our university hospital. Within the last days, she worked as a nurse in that ER, responsible for taking care of patients with novel influenza and also executing screening-examinations of suspicious cases.</p></div><div type="abstract" xml:lang="en"><p><b>INVESTIGATIONS</b></p><p>Patient in a reduced condition of health. C-reactive protein was significantly elevated (6.6 mg/dl - norm < 0.5). A PCR carried out on the admission day revealed a highly positive reaction (CT:19.29).</p></div><div type="abstract" xml:lang="en"><p><b>DIAGNOSIS, TREATMENT AND COURSE</b></p><p>Due to positive PCR laboratory report for H1N1/2009 and multiple occupational contacts with H1N1/2009 patients, therapy with neuraminidase inhibitor was started. After a five-day antiviral therapy and clinical signs of recovery, PCR was negative on the sixth treatment day.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>Health care workers (HCWs) are at risk of occupational exposure to influenza. Against the backdrop of the spread of H1N1 (2009) appropriate protective measures should be implemented to reduce the risk for transmission in health-care settings. The acquisition of epidemiologic data of occupational infections in Germany ought to be optimized. Required protective measures should be evaluated with regard to practicability and effectiveness.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">19908176</PMID><DateCompleted><Year>2009</Year><Month>12</Month><Day>01</Day></DateCompleted><DateRevised><Year>2009</Year><Month>11</Month><Day>20</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1439-4413</ISSN><JournalIssue CitedMedium="Internet"><Volume>134</Volume><Issue>48</Issue><PubDate><Year>2009</Year><Month>Nov</Month></PubDate></JournalIssue><Title>Deutsche medizinische Wochenschrift (1946)</Title><ISOAbbreviation>Dtsch. Med. Wochenschr.</ISOAbbreviation></Journal><ArticleTitle>[Novel influenza H1N1/2009: virus transmission among health care worker].</ArticleTitle><Pagination><MedlinePgn>2443-6</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1055/s-0029-1242012</ELocationID><Abstract><AbstractText Label="HISTORY AND ADMISSION FINDINGS" NlmCategory="METHODS">A 27-year-old female presented with fever (40 C) and infection of the upper respiratory tract in an emergency room (ER) department of our university hospital. Within the last days, she worked as a nurse in that ER, responsible for taking care of patients with novel influenza and also executing screening-examinations of suspicious cases.</AbstractText><AbstractText Label="INVESTIGATIONS" NlmCategory="METHODS">Patient in a reduced condition of health. C-reactive protein was significantly elevated (6.6 mg/dl - norm < 0.5). A PCR carried out on the admission day revealed a highly positive reaction (CT:19.29).</AbstractText><AbstractText Label="DIAGNOSIS, TREATMENT AND COURSE" NlmCategory="METHODS">Due to positive PCR laboratory report for H1N1/2009 and multiple occupational contacts with H1N1/2009 patients, therapy with neuraminidase inhibitor was started. After a five-day antiviral therapy and clinical signs of recovery, PCR was negative on the sixth treatment day.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Health care workers (HCWs) are at risk of occupational exposure to influenza. Against the backdrop of the spread of H1N1 (2009) appropriate protective measures should be implemented to reduce the risk for transmission in health-care settings. The acquisition of epidemiologic data of occupational infections in Germany ought to be optimized. Required protective measures should be evaluated with regard to practicability and effectiveness.</AbstractText><CopyrightInformation>Georg Thieme Verlag KG Stuttgart, New York.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Wicker</LastName><ForeName>S</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Betriebsärztlicher Dienst, Klinikum der Johann Wolfgang Goethe-Universität Frankfurt. Sabine.Wicker@kgu.de</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rabenau</LastName><ForeName>H F</ForeName><Initials>HF</Initials></Author><Author ValidYN="Y"><LastName>Bickel</LastName><ForeName>M</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Wolf</LastName><ForeName>T</ForeName><Initials>T</Initials></Author><Author ValidYN="Y"><LastName>Brodt</LastName><ForeName>R</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Brandt</LastName><ForeName>C</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Berger</LastName><ForeName>A</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Doerr</LastName><ForeName>H W</ForeName><Initials>HW</Initials></Author><Author ValidYN="Y"><LastName>Lehmann</LastName><ForeName>R</ForeName><Initials>R</Initials></Author></AuthorList><Language>ger</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D004740">English Abstract</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><VernacularTitle>Neue Grippe H1N1/2009: Infektionsübertragung auf medizinisches Personal.</VernacularTitle><ArticleDate DateType="Electronic"><Year>2009</Year><Month>11</Month><Day>11</Day></ArticleDate></Article><MedlineJournalInfo><Country>Germany</Country><MedlineTA>Dtsch Med Wochenschr</MedlineTA><NlmUniqueID>0006723</NlmUniqueID><ISSNLinking>0012-0472</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005858" MajorTopicYN="N" Type="Geographic">Germany</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006282" MajorTopicYN="Y">Health Personnel</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017053" MajorTopicYN="N">Infection Control</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017758" MajorTopicYN="Y">Infectious Disease Transmission, Patient-to-Professional</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D053118" MajorTopicYN="Y">Influenza A Virus, H1N1 Subtype</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName><QualifierName UI="Q000635" MajorTopicYN="Y">transmission</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2009</Year><Month>11</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2009</Year><Month>11</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2009</Year><Month>12</Month><Day>16</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">19908176</ArticleId><ArticleId IdType="doi">10.1055/s-0029-1242012</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Allemagne</li></country><region><li>District de Darmstadt</li><li>Hesse (Land)</li></region><settlement><li>Francfort-sur-le-Main</li></settlement><orgName><li>Université Johann Wolfgang Goethe de Francfort-sur-le-Main</li></orgName></list><tree><noCountry><name sortKey="Berger, A" sort="Berger, A" uniqKey="Berger A" first="A" last="Berger">A. Berger</name><name sortKey="Bickel, M" sort="Bickel, M" uniqKey="Bickel M" first="M" last="Bickel">M. Bickel</name><name sortKey="Brandt, C" sort="Brandt, C" uniqKey="Brandt C" first="C" last="Brandt">C. Brandt</name><name sortKey="Brodt, R" sort="Brodt, R" uniqKey="Brodt R" first="R" last="Brodt">R. Brodt</name><name sortKey="Doerr, H W" sort="Doerr, H W" uniqKey="Doerr H" first="H W" last="Doerr">H W Doerr</name><name sortKey="Lehmann, R" sort="Lehmann, R" uniqKey="Lehmann R" first="R" last="Lehmann">R. Lehmann</name><name sortKey="Rabenau, H F" sort="Rabenau, H F" uniqKey="Rabenau H" first="H F" last="Rabenau">H F Rabenau</name><name sortKey="Wolf, T" sort="Wolf, T" uniqKey="Wolf T" first="T" last="Wolf">T. Wolf</name></noCountry><country name="Allemagne"><region name="Hesse (Land)"><name sortKey="Wicker, S" sort="Wicker, S" uniqKey="Wicker S" first="S" last="Wicker">S. Wicker</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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